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MATLAB and Python Interoperability

How to call Python libraries from MATLAB, call MATLAB functions from Python, and package MATLAB code as standalone Python modules.

Practical MATLABAdvanced10 min readJul 10, 2026
Analogies

Why Combine MATLAB and Python

MATLAB and Python have complementary strengths: MATLAB excels at rigorous numerical computing, signal processing, and its curated domain-specific toolboxes, while Python offers a vast general-purpose ecosystem for web scraping, deployment, and rapidly evolving machine-learning libraries. Rather than forcing a full rewrite in one language or the other, MATLAB provides direct interoperability in both directions, letting a project use each language for the part of the pipeline it's best suited for.

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Cricket analogy: Combining MATLAB's signal-processing strength with Python's web-scraping ecosystem to build a ball-tracking analytics pipeline is like pairing a specialist spin bowler with a specialist death-overs bowler — each contributes where they're strongest.

Calling Python from MATLAB

MATLAB lets you call Python functions and access Python objects directly using the py. prefix — for example, py.numpy.array([1 2 3]) — or by running arbitrary Python statements with pyrun, after pointing MATLAB at a specific interpreter with pyenv('Version', '/path/to/python'). Values returned from Python calls arrive in the MATLAB workspace as Python-typed objects (like py.numpy.ndarray), not native MATLAB types, so they typically need explicit conversion — e.g., double(pyResult) — before you can use them in ordinary MATLAB numeric operations.

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Cricket analogy: Calling py.numpy.array(runsPerOver) from MATLAB to hand ball-by-ball data to a Python NumPy function mirrors a team analyst exporting the raw scorecard to a specialist statistician's preferred software for a specific calculation.

matlab
% Calling Python from MATLAB
pyenv('Version', '/usr/bin/python3');
data = py.numpy.array([12, 45, 78, 23, 90]);
meanVal = double(py.numpy.mean(data));   % convert back to native MATLAB double
fprintf('Mean value: %.2f\n', meanVal);

Calling MATLAB from Python

The MATLAB Engine API for Python, used via matlab.engine.start_matlab(), starts (or connects to) a MATLAB session that a Python script can call functions on directly, such as eng.myFunction(arg1, arg2). This is the mirror image of calling Python from MATLAB: a Python-based application defers a specific calculation to a validated, existing MATLAB function rather than reimplementing that logic in Python, and the engine session behaves like a live, running MATLAB instance the Python process is communicating with.

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Cricket analogy: Starting a MATLAB engine session from Python with matlab.engine.start_matlab() to call a bowling-speed analysis function mirrors a Python-based match-day app dialing into a dedicated MATLAB analytics server for one specific calculation.

python
# Calling MATLAB from Python
import matlab.engine

eng = matlab.engine.start_matlab()
speed = eng.calculateBowlingSpeed(140.0, 22.5)  # velocity, release angle
print(f"Estimated ball speed: {speed:.2f} km/h")
eng.quit()

Data types don't map one-to-one across the boundary: a Python NumPy array returned to MATLAB arrives as a py.numpy.ndarray object, not a native double array, and must be explicitly converted (e.g., double(somePyArray)); conversely, a MATLAB matrix passed into Python via the Engine API becomes a nested matlab.double object, not a NumPy array, so wrap it with numpy.array(matlabArray) before using NumPy operations on it.

Packaging MATLAB Code for Python Deployment

MATLAB Compiler SDK's compiler.build.pythonPackage compiles a MATLAB function into a standalone Python package that end users install with pip install and call like any ordinary Python module, without needing a full MATLAB license — they only need the free, redistributable MATLAB Runtime installed. This is the deployment path of choice when a validated MATLAB algorithm needs to ship as part of a larger Python-based product, since it protects the underlying MATLAB source while making the algorithm callable from plain Python code.

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Cricket analogy: Packaging a MATLAB bowling-analysis function into a standalone Python package with MATLAB Compiler SDK mirrors licensing a proprietary ball-tracking algorithm to broadcasters who don't own the underlying hardware, just the analysis output.

MATLAB Compiler SDK's compiler.build.pythonPackage can package a MATLAB function into a standalone Python package that end users install with pip install, without requiring them to own a MATLAB license — but it does require the MATLAB Runtime to be installed, and the generated package's supported Python version must match what MATLAB Compiler SDK targets for that MATLAB release.

  • MATLAB and Python each have ecosystem strengths — MATLAB for numerical/signal-processing rigor and toolboxes, Python for general-purpose scripting and ML/web libraries — and interoperability lets you use both without rewriting code.
  • Call Python from MATLAB using the py. prefix (e.g., py.numpy.array(...)) or pyrun, after configuring the interpreter with pyenv.
  • Data returned from Python arrives as Python-typed objects (e.g., py.numpy.ndarray) and must be explicitly converted to native MATLAB types like double.
  • Call MATLAB from Python using the MATLAB Engine API (matlab.engine.start_matlab()), which starts or connects to a MATLAB session and lets you call MATLAB functions directly from Python code.
  • MATLAB matrices passed into Python become matlab.double objects, not NumPy arrays, and need explicit conversion with numpy.array(...) before using NumPy operations.
  • MATLAB Compiler SDK's compiler.build.pythonPackage packages MATLAB functions into installable Python packages, letting end users run them via pip install with the MATLAB Runtime instead of a full MATLAB license.
  • Always verify Python and MATLAB version compatibility (pyenv reports the active Python version) since each MATLAB release supports only specific Python versions.

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